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Novel Class of Viral Ankyrin Proteins Targeting the Host E3 Ubiquitin Ligase Cullin-2

Ankyrin repeat (ANK) domains are among the most abundant motifs in eukaryotic proteins. ANK proteins are rare amongst viruses, with the exception of poxviruses, which presumably acquired them from the host via horizontal gene transfer. The architecture of poxvirus ANK proteins is, however, different...

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Detalles Bibliográficos
Autores principales: Odon, Valerie, Georgana, Iliana, Holley, Joe, Morata, Jordi, Maluquer de Motes, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232478/
https://www.ncbi.nlm.nih.gov/pubmed/30258003
http://dx.doi.org/10.1128/JVI.01374-18