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Seneca Valley Virus Exploits TEM8, a Collagen Receptor Implicated in Tumor Growth

Recent studies reveal that Seneca Valley Virus (SVV) exploits tumor endothelial marker 8 (TEM8) for cellular entry, the same surface receptor pirated by bacterial-derived anthrax toxin. This observation is particularly significant as SVV is a known oncolytic virus which selectively infects and kills...

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Detalles Bibliográficos
Autores principales: Evans, David J., Wasinger, Alexa M., Brey, Robert N., Dunleavey, James M., St. Croix, Brad, Bann, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232524/
https://www.ncbi.nlm.nih.gov/pubmed/30460197
http://dx.doi.org/10.3389/fonc.2018.00506