The SMAC Mimetic APG-1387 Sensitizes Immune-Mediated Cell Apoptosis in Hepatocellular Carcinoma

The inhibitor of apoptosis protein (IAP) genes are frequently overexpressed in malignancies. Second mitochondria-derived activator of caspase (SMAC) mimetics, which target IAPs, have potential to trigger cancer cell death and sensitize tumor cells to cytotoxic therapy. The aim of this study was to i...

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Detalles Bibliográficos
Autores principales: Chen, Zide, Chen, Jiehua, Liu, Hongyan, Dong, Wei, Huang, Xuan, Yang, Dajun, Hou, Jinlin, Zhang, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232623/
https://www.ncbi.nlm.nih.gov/pubmed/30459627
http://dx.doi.org/10.3389/fphar.2018.01298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232623/
https://www.ncbi.nlm.nih.gov/pubmed/30459627
http://dx.doi.org/10.3389/fphar.2018.01298

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