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Rheumatoid Arthritis-Associated Autoimmunity Due to Aggregatibacter actinomycetemcomitans and Its Resolution With Antibiotic Therapy
Background: Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative coccobacillus recognized as a pathogen in periodontitis and infective endocarditis. By producing a toxin (leukotoxin A, LtxA) that triggers global hypercitrullination in neutrophils, Aa has been recently linked to rheumatoid a...
Autores principales: | Mukherjee, Amarshi, Jantsch, Vanessa, Khan, Rida, Hartung, Wolfgang, Fischer, René, Jantsch, Jonathan, Ehrenstein, Boris, Konig, Maximilian F., Andrade, Felipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232707/ https://www.ncbi.nlm.nih.gov/pubmed/30459755 http://dx.doi.org/10.3389/fimmu.2018.02352 |
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