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Monogenic Lupus: A Developing Paradigm of Disease

Monogenic lupus is a form of systemic lupus erythematosus (SLE) that occurs in patients with a single gene defect. This rare variant of lupus generally presents with early onset severe disease, especially affecting the kidneys and central nervous system. To date, a significant number of genes have b...

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Detalles Bibliográficos
Autores principales: Alperin, Jessie M., Ortiz-Fernández, Lourdes, Sawalha, Amr H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232876/
https://www.ncbi.nlm.nih.gov/pubmed/30459768
http://dx.doi.org/10.3389/fimmu.2018.02496