Blockade of Rostral Ventrolateral Medulla Apelin Receptors Does Not Attenuate Arterial Pressure in SHR and (L)-NAME-Induced Hypertensive Rats

Dysfunction of the apelinergic system, comprised of the neuropeptide apelin mediating its effects via the G protein-coupled apelin receptor (APJ), may underlie the onset of cardiovascular disease such as hypertension. Apelin expression is increased in the rostral ventrolateral medulla (RVLM) in spon...

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Detalles Bibliográficos
Autores principales: Griffiths, Philip R., Lolait, Stephen J., Pearce, Louise E., McBryde, Fiona D., Paton, Julian F. R., O’Carroll, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232890/
https://www.ncbi.nlm.nih.gov/pubmed/30459635
http://dx.doi.org/10.3389/fphys.2018.01488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232890/
https://www.ncbi.nlm.nih.gov/pubmed/30459635
http://dx.doi.org/10.3389/fphys.2018.01488

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