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Blockade of Rostral Ventrolateral Medulla Apelin Receptors Does Not Attenuate Arterial Pressure in SHR and (L)-NAME-Induced Hypertensive Rats

Dysfunction of the apelinergic system, comprised of the neuropeptide apelin mediating its effects via the G protein-coupled apelin receptor (APJ), may underlie the onset of cardiovascular disease such as hypertension. Apelin expression is increased in the rostral ventrolateral medulla (RVLM) in spon...

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Detalles Bibliográficos
Autores principales:	Griffiths, Philip R., Lolait, Stephen J., Pearce, Louise E., McBryde, Fiona D., Paton, Julian F. R., O’Carroll, Anne-Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232890/ https://www.ncbi.nlm.nih.gov/pubmed/30459635 http://dx.doi.org/10.3389/fphys.2018.01488

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