Cargando…

Psoralen Induced Liver Injury by Attenuating Liver Regenerative Capability

Psoralen is a major component of the common traditional Chinese medicine Fructus Psoraleae (FP). In this study, we focused on psoralen to explore FP-induced hepatotoxicity and the underlying mechanisms. The acute oral median lethal dose of psoralen in ICR mice was determined to be 1,673 mg/kg. C57BL...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Wang, Chen, Xi, Zhao, Guolin, Xu, Dengqiu, Jiang, Zhenzhou, Zhang, Luyong, Wang, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232894/ https://www.ncbi.nlm.nih.gov/pubmed/30459602 http://dx.doi.org/10.3389/fphar.2018.01179

Ejemplares similares

Effect of Adoptive Transfer or Depletion of Regulatory T Cells on Triptolide-induced Liver Injury
por: Wang, Xinzhi, et al.
Publicado: (2016)

Bicyclol Attenuates Acute Liver Injury by Activating Autophagy, Anti-Oxidative and Anti-Inflammatory Capabilities in Mice
por: Zhao, Tian-Ming, et al.
Publicado: (2020)

Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats
por: Yang, Jing, et al.
Publicado: (2017)

A Review of the Pharmacological Properties of Psoralen
por: Ren, Yali, et al.
Publicado: (2020)

Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata
por: Gao, Dan, et al.
Publicado: (2016)

Sex-Related Differences of Lipid Metabolism Induced by Triptolide: The Possible Role of the LXRα/SREBP-1 Signaling Pathway
por: Jiang, Zhenzhou, et al.
Publicado: (2016)

Investigating the CYP2E1 Potential Role in the Mechanisms Behind INH/LPS-Induced Hepatotoxicity
por: Hassan, Hozeifa M., et al.
Publicado: (2018)

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder
por: Xia, Qing, et al.
Publicado: (2018)

Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway in vitro and in vivo
por: Ding, Yan, et al.
Publicado: (2018)

Fisetin Prevents Acetaminophen-Induced Liver Injury by Promoting Autophagy
por: Zhang, Jiaqi, et al.
Publicado: (2020)

Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity
por: Xiong, Weichen, et al.
Publicado: (2021)

Metabolomic Profiling for Histologically Fibrotic Stage in Chronic Drug-Induced Liver Injury
por: He, Xian, et al.
Publicado: (2022)

Proteomics analysis reveals novel insights into the mechanism of hepatotoxicity induced by Tripterygium wilfordii multiglycoside in mice
por: Miao, Yingying, et al.
Publicado: (2022)

Apigenin Prevents Acetaminophen-Induced Liver Injury by Activating the SIRT1 Pathway
por: Zhao, Licong, et al.
Publicado: (2020)

Beware of the Potential Risks for Polygoni Multiflori Caulis-Induced Liver Injury
por: Kong, Wei-Song, et al.
Publicado: (2022)

Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects
por: Liu, Zhaoguo, et al.
Publicado: (2022)

Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury
por: Zhou, Yitian, et al.
Publicado: (2019)

Ferrostatin-1 Ameliorates Liver Dysfunction via Reducing Iron in Thioacetamide-induced Acute Liver Injury in Mice
por: Jiang, Hui, et al.
Publicado: (2022)

Molecular Biomarkers in Drug-Induced Liver Injury: Challenges and Future Perspectives
por: Fu, Siyu, et al.
Publicado: (2020)

Protective Property of Scutellarin Against Liver Injury Induced by Carbon Tetrachloride in Mice
por: Miao, Zhimin, et al.
Publicado: (2021)

Triptolide increases resistance to bile duct ligation-induced liver injury and fibrosis in mice by inhibiting RELB
por: Yuan, Zihang, et al.
Publicado: (2022)

Screening for Susceptibility-Related Biomarkers of Diclofenac-Induced Liver Injury in Rats Using Metabolomics
por: Tu, Can, et al.
Publicado: (2021)

Dexamethasone Pretreatment Alleviates Isoniazid/Lipopolysaccharide Hepatotoxicity: Inhibition of Inflammatory and Oxidative Stress
por: Hassan, Hozeifa M., et al.
Publicado: (2017)

Research Progress of Pharmacogenomics in Drug-Induced Liver Injury
por: Shao, Qihui, et al.
Publicado: (2021)

Phillygenin Attenuates Carbon Tetrachloride-Induced Liver Fibrosis via Modulating Inflammation and Gut Microbiota
por: Wang, Cheng, et al.
Publicado: (2021)

Chronic Drug-Induced Liver Injury: Updates and Future Challenges
por: Wang, Qiaoling, et al.
Publicado: (2021)

Interleukin-35 Attenuates D-Galactosamine/Lipopolysaccharide-Induced Liver Injury via Enhancing Interleukin-10 Production in Kupffer Cells
por: Zheng, Xing-Feng, et al.
Publicado: (2018)

A potential therapeutic effect of catalpol in Duchenne muscular dystrophy revealed by binding with TAK1
por: Xu, Dengqiu, et al.
Publicado: (2020)

Aripiprazole-induced liver injury: a spontaneous reporting database study
por: Gao, Yunjuan, et al.
Publicado: (2023)

Inflammatory stress potentiates emodin-induced liver injury in rats
por: Tu, Can, et al.
Publicado: (2015)

Regenerative responses to liver injury
por: Michalopoulos, George K
Publicado: (2014)

Kaempferol attenuates nonalcoholic steatohepatitis by regulating serum and liver bile acid metabolism
por: Lu, Yifei, et al.
Publicado: (2022)

Advances in the study of acetaminophen-induced liver injury
por: Li, Xinghui, et al.
Publicado: (2023)

Autoimmunity associates with severity of illness in elderly patients with drug-induced liver injury
por: Xiong, Yu-Ting, et al.
Publicado: (2023)

Pharmacotherapies for Drug-Induced Liver Injury: A Current Literature Review
por: Li, Meng, et al.
Publicado: (2022)

Dual Role of Dietary Curcumin Through Attenuating AFB(1)-Induced Oxidative Stress and Liver Injury via Modulating Liver Phase-I and Phase-II Enzymes Involved in AFB(1) Bioactivation and Detoxification
por: Muhammad, Ishfaq, et al.
Publicado: (2018)

Physcion Protects Against Ethanol-Induced Liver Injury by Reprogramming of Circadian Clock
por: Yao, Youli, et al.
Publicado: (2020)

A review of herb-induced liver injury in mainland china
por: Yang, Yan, et al.
Publicado: (2022)

Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver
por: Cheng, Zhuo, et al.
Publicado: (2022)

Corrigendum: Inflammatory Stress Potentiates Emodin-Induced Liver Injury in Rats
por: Tu, Can, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j80fa67t8rbdl4gbrcap6471ui