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Rationale for an Association Between PD1 Checkpoint Inhibition and Therapeutic Vaccination Against HIV
The pathogenesis of HIV immunodeficiency is mainly dependent on the cytopatic effects exerted by the virus against infected CD4+ T cells. However, CD4+ T cell loss cannot be the only pathogenic factor since severe opportunistic infections may develop in HIV infected patients with normal CD4+ T cell...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232923/ https://www.ncbi.nlm.nih.gov/pubmed/30459765 http://dx.doi.org/10.3389/fimmu.2018.02447 |