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A Novel Glycoproteomics Workflow Reveals Dynamic O-GlcNAcylation of COPγ1 as a Candidate Regulator of Protein Trafficking

O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form of protein glycosylation in animals and plants. In humans, dysregulation of O-GlcNAcylation occurs in a wide range of diseases, including cancer, diabetes, and neurodegeneration. Since its discovery more than 3...

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Detalles Bibliográficos
Autores principales: Cox, Nathan J., Luo, Peter M., Smith, Timothy J., Bisnett, Brittany J., Soderblom, Erik J., Boyce, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232944/
https://www.ncbi.nlm.nih.gov/pubmed/30459710
http://dx.doi.org/10.3389/fendo.2018.00606