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TOR complex 2–regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain–containing proteins located at plasma membrane–endoplasmic reticulum contact sites
In our proteome-wide screen, Ysp2 (also known as Lam2/Ltc4) was identified as a likely physiologically relevant target of the TOR complex 2 (TORC2)–dependent protein kinase Ypk1 in the yeast Saccharomyces cerevisiae. Ysp2 was subsequently shown to be one of a new family of sterol-binding proteins lo...
Autores principales: | Roelants, Françoise M., Chauhan, Neha, Muir, Alexander, Davis, Jameson C., Menon, Anant K., Levine, Timothy P., Thorner, Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232965/ https://www.ncbi.nlm.nih.gov/pubmed/29927351 http://dx.doi.org/10.1091/mbc.E18-04-0229 |
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