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Interstitial flow promotes macrophage polarization toward an M2 phenotype

Tumor tissues are characterized by an elevated interstitial fluid flow from the tumor to the surrounding stroma. Macrophages in the tumor microenvironment are key contributors to tumor progression. While it is well established that chemical stimuli within the tumor tissues can alter macrophage behav...

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Detalles Bibliográficos
Autores principales: Li, Ran, Serrano, Jean Carlos, Xing, Hao, Lee, Tara A., Azizgolshani, Hesham, Zaman, Muhammad, Kamm, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232969/
https://www.ncbi.nlm.nih.gov/pubmed/29995595
http://dx.doi.org/10.1091/mbc.E18-03-0164