Xiaoaiping Induces Developmental Toxicity in Zebrafish Embryos Through Activation of ER Stress, Apoptosis and the Wnt Pathway

The aim of the study was to determine the developmental toxicity of the traditional Chinese medicine Xiaoaiping (XAP) and to investigate its underlying mechanism of action. Zebrafish embryos were incubated with 0.4, 0.8, 1.2, and 1.6 mg/mL XAP. Endpoints such as mortality, hatching rate, malformatio...

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Detalles Bibliográficos
Autores principales: Li, Juanjuan, Zhang, Yun, Liu, Kechun, He, Qiuxia, Sun, Chen, Han, Jian, Han, Liwen, Tian, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233021/
https://www.ncbi.nlm.nih.gov/pubmed/30459614
http://dx.doi.org/10.3389/fphar.2018.01250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233021/
https://www.ncbi.nlm.nih.gov/pubmed/30459614
http://dx.doi.org/10.3389/fphar.2018.01250

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