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Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential
Increased tissue stiffness is a classic characteristic of solid tumors. One of the major contributing factors is increased density of collagen fibers in the extracellular matrix (ECM). Here, we investigate how cancer cells biomechanically interact with and respond to the stiffness of the ECM. Probin...
Autores principales: | Wullkopf, Lena, West, Ann-Katrine V., Leijnse, Natascha, Cox, Thomas R., Madsen, Chris D., Oddershede, Lene B., Erler, Janine T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233061/ https://www.ncbi.nlm.nih.gov/pubmed/30091653 http://dx.doi.org/10.1091/mbc.E18-05-0319 |
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