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WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis

The mitogen-activated protein kinases (MAPKs) regulate a variety of cellular processes. The three main MAPK cascades are the extracellular signal-regulated kinases (ERK), c-Jun N-terminal kinase (JNK), and p38 kinases. A typical MAPK cascade is composed of MAP3K-MAP2K-MAPK kinases that are held by s...

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Detalles Bibliográficos
Autores principales:	Prinz, Elad, Aviram, Sharon, Aronheim, Ami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233063/ https://www.ncbi.nlm.nih.gov/pubmed/30091641 http://dx.doi.org/10.1091/mbc.E17-08-0504

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