Isolation and characterization of NY-ESO-1–specific T cell receptors restricted on various MHC molecules

Tumor-specific T cell receptor (TCR) gene transfer enables specific and potent immune targeting of tumor antigens. Due to the prevalence of the HLA-A2 MHC class I supertype in most human populations, the majority of TCR gene therapy trials targeting public antigens have employed HLA-A2–restricted TC...

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Detalles Bibliográficos
Autores principales: Bethune, Michael T., Li, Xiao-Hua, Yu, Jiaji, McLaughlin, Jami, Cheng, Donghui, Mathis, Colleen, Moreno, Blanca Homet, Woods, Katherine, Knights, Ashley J., Garcia-Diaz, Angel, Wong, Stephanie, Hu-Lieskovan, Siwen, Puig-Saus, Cristina, Cebon, Jonathan, Ribas, Antoni, Yang, Lili, Witte, Owen N., Baltimore, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233129/
https://www.ncbi.nlm.nih.gov/pubmed/30348802
http://dx.doi.org/10.1073/pnas.1810653115

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