Cargando…

CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsis

High-density cholesterol (HDL-C) levels are influenced by genetic variation in several genes. Low levels of HDL-C have been associated with increased risk of acute kidney injury (AKI). We investigated whether genetic polymorphisms in ten genes known to regulate HDL-C levels are associated with both...

Descripción completa

Detalles Bibliográficos
Autores principales:	Genga, Kelly Roveran, Trinder, Mark, Kong, HyeJin Julia, Li, Xuan, Leung, Alex K. K., Shimada, Tadanaga, Walley, Keith R., Russell, James A., Francis, Gordon A., Brunham, Liam R., Boyd, John H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233165/ https://www.ncbi.nlm.nih.gov/pubmed/30425299 http://dx.doi.org/10.1038/s41598-018-35261-2

Ejemplares similares

Reduced Proprotein convertase subtilisin/kexin 9 (PCSK9) function increases lipoteichoic acid clearance and improves outcomes in Gram positive septic shock patients
por: Leung, Alex K. K., et al.
Publicado: (2019)

Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease
por: Trinder, Mark, et al.
Publicado: (2020)

Effects of Obesity and Family History of Diabetes on the Association of CETP rs6499861 with HDL-C Level in Korean Populations
por: Sull, Jae Woong, et al.
Publicado: (2019)

Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
por: Ølnes, Åsa Schawlann, et al.
Publicado: (2023)

eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency
por: Gomaraschi, Monica, et al.
Publicado: (2014)

CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet
por: Zhu, Lin, et al.
Publicado: (2018)

Segregation of LIPG, CETP, and GALNT2 Mutations in Caucasian Families with Extremely High HDL Cholesterol
por: Tietjen, Ian, et al.
Publicado: (2012)

The Association of Common SNPs and Haplotypes in CETP Gene with HDL Cholesterol Levels in Latvian Population
por: Radovica, Ilze, et al.
Publicado: (2013)

Metabolism of PLTP, CETP, and LCAT on multiple HDL sizes using the Orbitrap Fusion Lumos
por: Singh, Sasha A., et al.
Publicado: (2021)

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C
por: van Leeuwen, Elisabeth M, et al.
Publicado: (2015)

HDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation
por: Zhang, Meng, et al.
Publicado: (2015)

The lipid substrate preference of CETP controls the biochemical properties of HDL in fat/cholesterol-fed hamsters
por: Morton, Richard E., et al.
Publicado: (2021)

Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease
por: Trinder, Mark, et al.
Publicado: (2020)

Impact of PCSK9 loss-of-function genotype on 1-year mortality and recurrent infection in sepsis survivors
por: Genga, Kelly Roveran, et al.
Publicado: (2018)

The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration: Insights from the IMPROVE Study
por: Colombo, Gualtiero I., et al.
Publicado: (2021)

Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol
por: Kühnast, Susan, et al.
Publicado: (2013)

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors
por: Mabuchi, Hiroshi, et al.
Publicado: (2014)

Cholesteryl Ester Transfer Protein (CETP) Polymorphisms Affect mRNA Splicing, HDL Levels, and Sex-Dependent Cardiovascular Risk
por: Papp, Audrey C., et al.
Publicado: (2012)

Patient Perspectives Regarding Genetic Testing for Familial Hypercholesterolemia
por: Marchand, Miles, et al.
Publicado: (2021)

Cholesteryl ester transfer protein (CETP), HDL capacity of receiving cholesterol and status of inflammatory cytokines in patients with severe heart failure
por: Martinelli, Ana Elisa M., et al.
Publicado: (2018)

Impact of variants in CETP and apo AI genes on serum HDL cholesterol levels in men and women from the Polish population
por: Włodarczyk, Marta, et al.
Publicado: (2016)

The Effect of Haplotypes in the CETP and LIPC Genes on the Triglycerides to HDL-C Ratio and Its Components in the Roma and Hungarian General Populations
por: Piko, Peter, et al.
Publicado: (2020)

Association of ESR1 (rs2234693 and rs9340799), CETP (rs708272), MTHFR (rs1801133 and rs2274976) and MS (rs185087) polymorphisms with Coronary Artery Disease (CAD)
por: Raina, Jyotdeep Kour, et al.
Publicado: (2020)

The rs4783961 and rs708272 genetic variants of the CETP gene are associated with coronary artery disease, but not with restenosis after coronary stenting
por: Vargas-Alarcón, Gilberto, et al.
Publicado: (2022)

A reduction of CETP activity, not an increase, is associated with modestly impaired postprandial lipemia and increased HDL-Cholesterol in adult asymptomatic women
por: Parra, Eliane S, et al.
Publicado: (2011)

High-Density Lipoprotein (HDL) Particle Subpopulations in Heterozygous Cholesteryl Ester Transfer Protein (CETP) Deficiency: Maintenance of Antioxidative Activity
por: Chantepie, Sandrine, et al.
Publicado: (2012)

Low CETP activity and unique composition of large VLDL and small HDL in women giving birth to small-for-gestational age infants
por: Roland, Marie Cecilie Paasche, et al.
Publicado: (2021)

Association Between Lipids, Lipoproteins Composition of HDL Particles and Triglyceride-Rich Lipoproteins, and LCAT and CETP Activity in Post-renal Transplant Patients
por: Kimak, Elżbieta, et al.
Publicado: (2013)

Consumption of policosanol enhances HDL functionality via CETP inhibition and reduces blood pressure and visceral fat in young and middle-aged subjects
por: Kim, Jae-Yong, et al.
Publicado: (2017)

Pharmacological Inhibition of CETP (Cholesteryl Ester Transfer Protein) Increases HDL (High-Density Lipoprotein) That Contains ApoC3 and Other HDL Subspecies Associated With Higher Risk of Coronary Heart Disease
por: Furtado, Jeremy D., et al.
Publicado: (2021)

Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis
por: Lee, Joseph G. H., et al.
Publicado: (2018)

Sex Differences in the Presentation, Treatment, and Outcome of Patients With Familial Hypercholesterolemia
por: Ryzhaya, Natalia, et al.
Publicado: (2021)

Subclinical AKI is still AKI
por: Ronco, Claudio, et al.
Publicado: (2012)

The minor C-allele of the rs2014355 variant in ACADS gene is associated with exercise-induced increase in HDL cholesterol levels in Taiwanese adults
por: Yang, Tzi-Peng, et al.
Publicado: (2021)

Xanthohumol Prevents Atherosclerosis by Reducing Arterial Cholesterol Content via CETP and Apolipoprotein E in CETP-Transgenic Mice
por: Hirata, Hiroshi, et al.
Publicado: (2012)

Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia
por: Trinder, Mark, et al.
Publicado: (2020)

Polymorphisms in LPL, CETP, and HL protect HIV-infected patients from atherogenic dyslipidemia in an allele-dose-dependent manner
por: Echeverría, Patricia, et al.
Publicado: (2014)

HDL-cholesterol concentration in pregnant Chinese Han women of late second trimester associated with genetic variants in CETP, ABCA1, APOC3, and GALNT2
por: Cui, Mingxuan, et al.
Publicado: (2017)

Association of RS708272 (CETP Gene Variant) with Lipid Profile Parameters and the Risk of Myocardial Infarction in the White Population of Western Siberia
por: Semaev, Sergey, et al.
Publicado: (2019)

IL-17A rs1974226 GG genotype is associated with increased susceptibility to Gram-positive infection and mortality of severe sepsis
por: Nakada, T, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_m5vrvb71st95dpnsvrrbut8fe6