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Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B

Calpain-10 (CAPN10) is the calpain family protease identified as the first candidate susceptibility gene for type 2 diabetes mellitus (T2DM). However, the detailed molecular mechanism has not yet been elucidated. Here we report that CAPN10 processes microtubule associated protein 1 (MAP1) family pro...

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Detalles Bibliográficos
Autores principales: Hatta, Tomohisa, Iemura, Shun-ichiro, Ohishi, Tomokazu, Nakayama, Hiroshi, Seimiya, Hiroyuki, Yasuda, Takao, Iizuka, Katsumi, Fukuda, Mitsunori, Takeda, Jun, Natsume, Tohru, Horikawa, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233169/
https://www.ncbi.nlm.nih.gov/pubmed/30425305
http://dx.doi.org/10.1038/s41598-018-35204-x

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