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Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect
Climate change is affecting biodiversity, but proximate drivers remain poorly understood. Here, we examine how experimental heatwaves impact on reproduction in an insect system. Male sensitivity to heat is recognised in endotherms, but ectotherms have received limited attention, despite comprising m...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233181/ https://www.ncbi.nlm.nih.gov/pubmed/30425248 http://dx.doi.org/10.1038/s41467-018-07273-z |
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author | Sales, Kris Vasudeva, Ramakrishnan Dickinson, Matthew E. Godwin, Joanne L. Lumley, Alyson J. Michalczyk, Łukasz Hebberecht, Laura Thomas, Paul Franco, Aldina Gage, Matthew J. G. |
author_facet | Sales, Kris Vasudeva, Ramakrishnan Dickinson, Matthew E. Godwin, Joanne L. Lumley, Alyson J. Michalczyk, Łukasz Hebberecht, Laura Thomas, Paul Franco, Aldina Gage, Matthew J. G. |
author_sort | Sales, Kris |
collection | PubMed |
description | Climate change is affecting biodiversity, but proximate drivers remain poorly understood. Here, we examine how experimental heatwaves impact on reproduction in an insect system. Male sensitivity to heat is recognised in endotherms, but ectotherms have received limited attention, despite comprising most of biodiversity and being more influenced by temperature variation. Using a flour beetle model system, we find that heatwave conditions (5 to 7 °C above optimum for 5 days) damaged male, but not female, reproduction. Heatwaves reduce male fertility and sperm competitiveness, and successive heatwaves almost sterilise males. Heatwaves reduce sperm production, viability, and migration through the female. Inseminated sperm in female storage are also damaged by heatwaves. Finally, we discover transgenerational impacts, with reduced reproductive potential and lifespan of offspring when fathered by males, or sperm, that had experienced heatwaves. This male reproductive damage under heatwave conditions provides one potential driver behind biodiversity declines and contractions through global warming. |
format | Online Article Text |
id | pubmed-6233181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-62331812018-11-14 Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect Sales, Kris Vasudeva, Ramakrishnan Dickinson, Matthew E. Godwin, Joanne L. Lumley, Alyson J. Michalczyk, Łukasz Hebberecht, Laura Thomas, Paul Franco, Aldina Gage, Matthew J. G. Nat Commun Article Climate change is affecting biodiversity, but proximate drivers remain poorly understood. Here, we examine how experimental heatwaves impact on reproduction in an insect system. Male sensitivity to heat is recognised in endotherms, but ectotherms have received limited attention, despite comprising most of biodiversity and being more influenced by temperature variation. Using a flour beetle model system, we find that heatwave conditions (5 to 7 °C above optimum for 5 days) damaged male, but not female, reproduction. Heatwaves reduce male fertility and sperm competitiveness, and successive heatwaves almost sterilise males. Heatwaves reduce sperm production, viability, and migration through the female. Inseminated sperm in female storage are also damaged by heatwaves. Finally, we discover transgenerational impacts, with reduced reproductive potential and lifespan of offspring when fathered by males, or sperm, that had experienced heatwaves. This male reproductive damage under heatwave conditions provides one potential driver behind biodiversity declines and contractions through global warming. Nature Publishing Group UK 2018-11-13 /pmc/articles/PMC6233181/ /pubmed/30425248 http://dx.doi.org/10.1038/s41467-018-07273-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Sales, Kris Vasudeva, Ramakrishnan Dickinson, Matthew E. Godwin, Joanne L. Lumley, Alyson J. Michalczyk, Łukasz Hebberecht, Laura Thomas, Paul Franco, Aldina Gage, Matthew J. G. Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect |
title | Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect |
title_full | Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect |
title_fullStr | Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect |
title_full_unstemmed | Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect |
title_short | Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect |
title_sort | experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233181/ https://www.ncbi.nlm.nih.gov/pubmed/30425248 http://dx.doi.org/10.1038/s41467-018-07273-z |
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