Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN

Ubiquitin-specific protease 14 (USP14) is one of the major proteasome-associated deubiquitinating enzymes critical for proteome homeostasis. However, substrates of USP14 remain largely unknown, hindering the understanding of its functional roles. Here we conduct a comprehensive proteome, ubiquitinom...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Jiang, Shangwen, Li, Min, Xiong, Xuelian, Zhu, Mingrui, Li, Duanzhuo, Zhao, Lei, Qian, Lili, Zhai, Linhui, Li, Jing, Lu, Han, Sun, Shengnan, Lin, Jiandie, Lu, Yan, Li, Xiaoying, Tan, Minjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233205/
https://www.ncbi.nlm.nih.gov/pubmed/30425250
http://dx.doi.org/10.1038/s41467-018-07185-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233205/
https://www.ncbi.nlm.nih.gov/pubmed/30425250
http://dx.doi.org/10.1038/s41467-018-07185-y

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