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RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation

BACKGROUND: The cellular response to ionizing radiation involves activation of p53-dependent pathways and activation of the atypical NF-κB pathway. The crosstalk between these two transcriptional networks include (co)regulation of common gene targets. Here we looked for novel genes potentially (co)r...

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Detalles Bibliográficos
Autores principales: Szołtysek, Katarzyna, Janus, Patryk, Zając, Gracjana, Stokowy, Tomasz, Walaszczyk, Anna, Widłak, Wiesława, Wojtaś, Bartosz, Gielniewski, Bartłomiej, Cockell, Simon, Perkins, Neil D., Kimmel, Marek, Widlak, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233266/
https://www.ncbi.nlm.nih.gov/pubmed/30419821
http://dx.doi.org/10.1186/s12864-018-5211-y