Intra-patient and inter-patient comparisons of DNA damage response biomarkers in Nasopharynx Cancer (NPC): analysis of NCC0901 randomised controlled trial of induction chemotherapy in locally advanced NPC

BACKGROUND: Inter-patient heterogeneity in radiation-induced DNA damage responses is proposed to reflect intrinsic variations in tumour and normal tissue radiation sensitivity, but the prediction of phenotype by a molecular biomarker is influenced by clinical confounders and assay reproducibility. H...

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Detalles Bibliográficos
Autores principales: Chua, Kevin Lee Min, Yeo, Eugenia Li Ling, Shihabudeen, Waseem Ahamed, Tan, Sze Huey, Shwe, Than Than, Ong, Enya Hui Wen, Lam, Paula Yeng Po, Soo, Khee Chee, Soong, Yoke Lim, Fong, Kam Weng, Tan, Terence Wee Kiat, Wee, Joseph Tien Seng, Chua, Melvin Lee Kiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233280/
https://www.ncbi.nlm.nih.gov/pubmed/30419858
http://dx.doi.org/10.1186/s12885-018-5005-2

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