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Anti-colorectal cancer effects of anti-p21Ras scFv delivered by the recombinant adenovirus KGHV500 and cytokine-induced killer cells

BACKGROUND: Colorectal cancer (CRC) is the most common type of gastrointestinal cancer. CRC gene therapy mediated by adenovirus holds great promise for the treatment of malignancies. However, intravenous delivery of adenovirus exhibits limited anti-tumor activity in vivo when used alone. METHODS: In...

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Detalles Bibliográficos
Autores principales: Liu, Fang-Rui, Bai, Shuang, Feng, Qiang, Pan, Xin-Yan, Song, Shu-Ling, Fang, Hong, Cui, Jing, Yang, Ju-Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233365/
https://www.ncbi.nlm.nih.gov/pubmed/30419845
http://dx.doi.org/10.1186/s12885-018-4989-y

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