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AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells

BACKGROUND: TNS2 is a focal adhesions protein and a binding partner for many proteins, including the receptor tyrosine kinase Axl. Although TNS2 can bind with Axl, the details of their interactions have not been elucidated. TNS2 is involved in IRS-1 signaling pathway. In this study, we confirmed the...

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Detalles Bibliográficos
Autores principales:	Cheng, Li-Chun, Chen, Yen-Lin, Cheng, An-Ning, Lee, Alan Yueh-Luen, Cho, Chun-Yu, Huang, Jhy-Shrian, Chuang, Shuang-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233515/ https://www.ncbi.nlm.nih.gov/pubmed/30419905 http://dx.doi.org/10.1186/s12929-018-0465-x

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