Cargando…

GAP43, a novel metastasis promoter in non-small cell lung cancer

BACKGROUND: Brain metastasis is an extremely serious sequela with a dismal prognosis in non-small cell lung cancer (NSCLC). The present study aimed to identify novel biomarkers and potential therapeutic targets for brain metastases of NSCLC. METHODS: We performed high-throughput Luminex assays to pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Fanrong, Ying, Lisha, Jin, Jiaoyue, Feng, Jianguo, Chen, Kaiyan, Huang, Minran, Wu, Yingxue, Yu, Herbert, Su, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233536/ https://www.ncbi.nlm.nih.gov/pubmed/30419922 http://dx.doi.org/10.1186/s12967-018-1682-5

Ejemplares similares

Non-disruptive mutation in TP53 DNA-binding domain is a beneficial factor of esophageal squamous cell carcinoma
por: Huang, Minran, et al.
Publicado: (2020)

The C-reactive protein/albumin ratio predicts long-term outcomes of patients with operable non-small cell lung cancer
por: Zhang, Fanrong, et al.
Publicado: (2016)

Complement component 7 (C7), a potential tumor suppressor, is correlated with tumor progression and prognosis
por: Ying, Lisha, et al.
Publicado: (2016)

Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway
por: Jin, Jiaoyue, et al.
Publicado: (2017)

Oncogenic Alterations in Histologically Negative Lymph Nodes Are Associated with Prognosis of Patients with Stage I Lung Adenocarcinoma
por: Tian, Yiping, et al.
Publicado: (2022)

Overcoming Linsitinib intrinsic resistance through inhibition of nuclear factor‐κB signaling in esophageal squamous cell carcinoma
por: Wu, Junzhou, et al.
Publicado: (2017)

Prognostic significance of programmed death-1 and programmed death-ligand 1 expression in patients with esophageal squamous cell carcinoma
por: Chen, Kaiyan, et al.
Publicado: (2016)

Tumor-Infiltrating CD4+ Lymphocytes Predict a Favorable Survival in Patients with Operable Esophageal Squamous Cell Carcinoma
por: Chen, Kaiyan, et al.
Publicado: (2017)

Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma
por: Su, Dan, et al.
Publicado: (2019)

Lung-molGPA Index Predicts Survival Outcomes of Non-Small-Cell Lung Cancer Patients with Synchronous or Metachronous Brain Metastases
por: Chen, Kaiyan, et al.
Publicado: (2020)

Immune-active tumor-adjacent tissues are associated with favorable prognosis in stage I lung squamous cell carcinoma
por: Ying, Lisha, et al.
Publicado: (2023)

Growth Associated Protein 43 (GAP-43) as a Novel Target for the Diagnosis, Treatment and Prevention of Epileptogenesis
por: Nemes, Ashley D., et al.
Publicado: (2017)

Gap Junction Protein Connexin43 Exacerbates Lung Vascular Permeability
por: O’Donnell, James J., et al.
Publicado: (2014)

Aberrant Expression of Cx43 Is Associated with the Peritoneal Metastasis of Gastric Cancer and Cx43-Mediated Gap Junction Enhances Gastric Cancer Cell Diapedesis from Peritoneal Mesothelium
por: Tang, Bo, et al.
Publicado: (2013)

Propofol attenuated liver transplantation-induced acute lung injury via connexin43 gap junction inhibition
por: Yuan, Dongdong, et al.
Publicado: (2016)

PRDX2 Promotes the Proliferation and Metastasis of Non-Small Cell Lung Cancer In Vitro and In Vivo
por: Chen, Yun, et al.
Publicado: (2020)

Immune microenvironment features and efficacy of PD‐1/PD‐L1 blockade in non‐small cell lung cancer patients with EGFR or HER2 exon 20 insertions
por: Chen, Kaiyan, et al.
Publicado: (2020)

Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation
por: Choudhary, Mayur, et al.
Publicado: (2015)

Cerebrospinal fluid GAP-43 in early multiple sclerosis
por: Rot, U, et al.
Publicado: (2018)

The effects of exercise on the GAP-43 expression in the spinal cord of arthritis-induced rats
por: Park, Soo-Jin, et al.
Publicado: (2016)

GAP-43 expression correlates with spinal motoneuron regeneration following root avulsion
por: Yuan, Qiuju, et al.
Publicado: (2009)

Impact of GAP-43, Cx43 and actin expression on the outcome and overall survival in diffuse and anaplastic gliomas
por: Krigers, Aleksandrs, et al.
Publicado: (2023)

AQP4 knockout promotes neurite outgrowth via upregulating GAP43 expression in infant rats with hypoxic‐ischemic brain injury
por: Dan, Qi‐Qin, et al.
Publicado: (2022)

Connexin43 and Bergmann Glial Gap Junctions in Cerebellar Function
por: Tanaka, Mika, et al.
Publicado: (2008)

Myosin VI facilitates connexin 43 gap junction accretion
por: Waxse, Bennett J., et al.
Publicado: (2017)

Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover
por: Solan, Joell L., et al.
Publicado: (2020)

Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology
por: Zhu, Yi
Publicado: (2022)

FOXM1 Promotes Lung Adenocarcinoma Invasion and Metastasis by Upregulating SNAIL
por: Wei, Ping, et al.
Publicado: (2015)

Knockdown of Nemo-like kinase promotes metastasis in non-small-cell lung cancer
por: Shi, Cui, et al.
Publicado: (2019)

Depressed Neuronal Growth Associated Protein (GAP)-43 Expression in the Small Intestines of Mice Experimentally Infected with Neodiplostomum seoulense
por: Pyo, Kyoung-Ho, et al.
Publicado: (2012)

CD47 Promotes Tumor Invasion and Metastasis in Non-small Cell Lung Cancer
por: Zhao, Hui, et al.
Publicado: (2016)

GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression
por: Lee, Ye Ji, et al.
Publicado: (2023)

GAP-43 ameliorates Podocyte injury by decreasing nuclear NFATc1 expression
por: Lian, Zhiwen, et al.
Publicado: (2021)

Conductance and Permeability of the Residual State of Connexin43 Gap Junction Channels
por: Bukauskas, Feliksas F., et al.
Publicado: (2002)

AGE-BSA down-regulates endothelial connexin43 gap junctions
por: Wang, Chi-Young, et al.
Publicado: (2011)

Structural plasticity of climbing fibers and the growth-associated protein GAP-43
por: Grasselli, Giorgio, et al.
Publicado: (2013)

Changes and Significance of SYP and GAP-43 Expression in the Hippocampus of CIH Rats
por: Zhu, Xiankun, et al.
Publicado: (2019)

Transient increase in CSF GAP-43 concentration after ischemic stroke
por: Sandelius, Åsa, et al.
Publicado: (2018)

Connexin-43 Gap Junctions Are Responsible for the Hypothalamic Tanycyte-Coupled Network
por: Recabal, Antonia, et al.
Publicado: (2018)

Prognostic value of cutaneous reinnervation with GAP-43 in oxaliplatin-induced neuropathy
por: Albayrak, Merve, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qed0r82fj2kr7i18sg8mbijuqt