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Successful response to the combination of immunotherapy and chemotherapy in cholangiocarcinoma with high tumour mutational burden and PD-L1 expression: a case report

BACKGROUND: Cholangiocarcinoma, or bile duct cancer, is a gastrointestinal cancer with limited therapeutic options and a poor outcome. Studies have revealed that some major driver genes are associated with cholangiocarcinoma, but no targeted therapies have been approved. Immune checkpoint inhibitors...

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Detalles Bibliográficos
Autores principales: Mou, Haibo, Yu, Lanfang, Liao, Qin, Hou, Xuehua, Wu, Yinfang, Cui, Qiang, Yan, Na, Ma, Ruobing, Wang, Lingjian, Yao, Ming, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233589/
https://www.ncbi.nlm.nih.gov/pubmed/30419854
http://dx.doi.org/10.1186/s12885-018-5021-2

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