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Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance
The global epidemic of drug resistant tuberculosis is a catastrophic example of how antimicrobial resistance is undermining the public health gains made possible by combination drug therapy. Recent evidence points to unappreciated bacterial factors that accelerate the emergence of drug resistance. I...
Autores principales: | Hicks, Nathan D., Yang, Jian, Zhang, Xiaobing, Zhao, Bing, Grad, Yonatan H., Liu, Liguo, Ou, Xichao, Chang, Zhili, Xia, Hui, Zhou, Yang, Wang, Shengfen, Dong, Jie, Sun, Lilian, Zhu, Yafang, Zhao, Yanlin, Jin, Qi, Fortune, Sarah M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233875/ https://www.ncbi.nlm.nih.gov/pubmed/30082724 http://dx.doi.org/10.1038/s41564-018-0218-3 |
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