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Dynamics of DNA Methylation Reprogramming Influenced by X Chromosome Dosage in Induced Pluripotent Stem Cells

How the epigenome of one cell type is remodeled during reprogramming into another unrelated type of cell remains unclear. Overexpression of transcription factors in somatic cells enables the induction of induced pluripotent stem cells (iPSCs). This process entails genome-wide remodeling of DNA methy...

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Detalles Bibliográficos
Autores principales:	Janiszewski, Adrian, Song, Juan, Vanheer, Lotte, De Geest, Natalie, Pasque, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233964/ https://www.ncbi.nlm.nih.gov/pubmed/30443643 http://dx.doi.org/10.1177/2516865718802931

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