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Methodological quality and synthesis of case series and case reports

Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, we present a framework for appraisal, synthesis and application of evidence derived from case repor...

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Autores principales: Murad, Mohammad Hassan, Sultan, Shahnaz, Haffar, Samir, Bazerbachi, Fateh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234235/
https://www.ncbi.nlm.nih.gov/pubmed/29420178
http://dx.doi.org/10.1136/bmjebm-2017-110853
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author Murad, Mohammad Hassan
Sultan, Shahnaz
Haffar, Samir
Bazerbachi, Fateh
author_facet Murad, Mohammad Hassan
Sultan, Shahnaz
Haffar, Samir
Bazerbachi, Fateh
author_sort Murad, Mohammad Hassan
collection PubMed
description Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, we present a framework for appraisal, synthesis and application of evidence derived from case reports and case series. We propose a tool to evaluate the methodological quality of case reports and case series based on the domains of selection, ascertainment, causality and reporting and provide signalling questions to aid evidence-based practitioners and systematic reviewers in their assessment. We suggest using evidence derived from case reports and case series to inform decision-making when no other higher level of evidence is available.
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spelling pubmed-62342352018-11-14 Methodological quality and synthesis of case series and case reports Murad, Mohammad Hassan Sultan, Shahnaz Haffar, Samir Bazerbachi, Fateh BMJ Evid Based Med General Medicine Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, we present a framework for appraisal, synthesis and application of evidence derived from case reports and case series. We propose a tool to evaluate the methodological quality of case reports and case series based on the domains of selection, ascertainment, causality and reporting and provide signalling questions to aid evidence-based practitioners and systematic reviewers in their assessment. We suggest using evidence derived from case reports and case series to inform decision-making when no other higher level of evidence is available. BMJ Publishing Group 2018-04 2018-02-02 /pmc/articles/PMC6234235/ /pubmed/29420178 http://dx.doi.org/10.1136/bmjebm-2017-110853 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle General Medicine
Murad, Mohammad Hassan
Sultan, Shahnaz
Haffar, Samir
Bazerbachi, Fateh
Methodological quality and synthesis of case series and case reports
title Methodological quality and synthesis of case series and case reports
title_full Methodological quality and synthesis of case series and case reports
title_fullStr Methodological quality and synthesis of case series and case reports
title_full_unstemmed Methodological quality and synthesis of case series and case reports
title_short Methodological quality and synthesis of case series and case reports
title_sort methodological quality and synthesis of case series and case reports
topic General Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234235/
https://www.ncbi.nlm.nih.gov/pubmed/29420178
http://dx.doi.org/10.1136/bmjebm-2017-110853
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