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Empagliflozin Increases Cardiac Energy Production in Diabetes: Novel Translational Insights Into the Heart Failure Benefits of SGLT2 Inhibitors

SGLT2 inhibitors have profound benefits on reducing heart failure and cardiovascular mortality in individuals with type 2 diabetes, although the mechanism(s) of this benefit remain poorly understood. Because changes in cardiac bioenergetics play a critical role in the pathophysiology of heart failur...

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Detalles Bibliográficos
Autores principales: Verma, Subodh, Rawat, Sonia, Ho, Kim L., Wagg, Cory S., Zhang, Liyan, Teoh, Hwee, Dyck, John E., Uddin, Golam M., Oudit, Gavin Y., Mayoux, Eric, Lehrke, Michael, Marx, Nikolaus, Lopaschuk, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234616/
https://www.ncbi.nlm.nih.gov/pubmed/30456329
http://dx.doi.org/10.1016/j.jacbts.2018.07.006