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Prophylactic intervention of probiotics (L.acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis

BACKGROUND: Colorectal cancer has been found to be attenuated either with prophylactic manipulation of gut microbiome with probiotics or celecoxib, a non-steroidal anti-inflammatory drug mainly by suppressing early pro-carcinogenic markers in various experimental studies. Therefore, the present stud...

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Detalles Bibliográficos
Autores principales: Sharaf, Leila Kaeid, Sharma, Mridul, Chandel, Deepika, Shukla, Geeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234654/
https://www.ncbi.nlm.nih.gov/pubmed/30424722
http://dx.doi.org/10.1186/s12885-018-4999-9