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BubR1 Insufficiency Impairs Affective Behavior and Memory Function in Mice

PURPOSE: Although aging causes functional declines in cognition, the molecular mechanism underlying these declines remains largely unknown. Recently, the spindle checkpoint kinase budding uninhibited by benzimidazole-related 1 (BubR1) has emerged as a key determinant for age-related pathology in var...

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Detalles Bibliográficos
Autores principales: Cho, Chang Hoon, Yang, Zhongxi, Yoo, Ki Hyun, Oliveros, Alfredo, Jang, Mi Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Continence Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234727/
https://www.ncbi.nlm.nih.gov/pubmed/30396261
http://dx.doi.org/10.5213/inj.1836218.109