Cargando…
BubR1 Insufficiency Impairs Affective Behavior and Memory Function in Mice
PURPOSE: Although aging causes functional declines in cognition, the molecular mechanism underlying these declines remains largely unknown. Recently, the spindle checkpoint kinase budding uninhibited by benzimidazole-related 1 (BubR1) has emerged as a key determinant for age-related pathology in var...
Autores principales: | Cho, Chang Hoon, Yang, Zhongxi, Yoo, Ki Hyun, Oliveros, Alfredo, Jang, Mi Hyeon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Continence Society
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234727/ https://www.ncbi.nlm.nih.gov/pubmed/30396261 http://dx.doi.org/10.5213/inj.1836218.109 |
Ejemplares similares
-
Age‐related decline in BubR1 impairs adult hippocampal neurogenesis
por: Yang, Zhongxi, et al.
Publicado: (2017) -
BubR1 and brain aging
por: Hussaini, Syed Mohammed Qasim, et al.
Publicado: (2017) -
sFRP3 inhibition improves age‐related cellular changes in BubR1 progeroid mice
por: Cho, Chang Hoon, et al.
Publicado: (2019) -
The progeroid gene BubR1 regulates axon myelination and motor function
por: Choi, Chan-Il, et al.
Publicado: (2016) -
Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence
por: Park, Sung-Hyun, et al.
Publicado: (2016)