Cargando…
The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling
Tumor initiation, progression, and therapeutic resistance have been proposed to originate from a subset of tumor cells, cancer stem cells (CSCs). However, the current understanding of the mechanisms involved in their self-renewal and tumor initiation capacity remains limited. Here, we report that ex...
Autores principales: | Lopez Almeida, Leonor, Sebbagh, Michael, Bertucci, François, Finetti, Pascal, Wicinski, Julien, Marchetto, Sylvie, Castellano, Rémy, Josselin, Emmanuelle, Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Borg, Jean-Paul, Santoni, Marie-Josée |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234904/ https://www.ncbi.nlm.nih.gov/pubmed/30344009 http://dx.doi.org/10.1016/j.stemcr.2018.09.008 |
Ejemplares similares
-
Production of CRISPRi-engineered primary human mammary epithelial cells with baboon envelope pseudotyped lentiviral vectors
por: Pastor, Sonia, et al.
Publicado: (2023) -
A genome‐wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells
por: Arfaoui, Abir, et al.
Publicado: (2019) -
BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells
por: Azzoni, Violette, et al.
Publicado: (2022) -
Breast cancer stem cells: tools and models to rely on
por: Charafe-Jauffret, Emmanuelle, et al.
Publicado: (2009) -
Targeting breast cancer stem cells: fishing season open!
por: Ginestier, Christophe, et al.
Publicado: (2010)