Loss of TXNIP enhances peritoneal metastasis and can be abrogated by dual TORC1/2 inhibition

Peritoneal metastasis (PM) is a debilitating consequence of multiple cancers. As cancer cells lose tonic signaling related to attachment dependence, critical morphologic shifts result in alteration of the transcriptome. Identifying key genes associated with this transformation may lead to targeted t...

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Detalles Bibliográficos
Autores principales: Spaeth-Cook, Douglas, Burch, Mark, Belton, Robin, Demoret, Bryce, Grosenbacher, Nicholas, David, Jason, Stets, Colin, Cohen, David, Shakya, Reena, Hays, John L., Chen, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235015/
https://www.ncbi.nlm.nih.gov/pubmed/30479697
http://dx.doi.org/10.18632/oncotarget.26281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235015/
https://www.ncbi.nlm.nih.gov/pubmed/30479697
http://dx.doi.org/10.18632/oncotarget.26281

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