Third party, umbilical cord blood derived regulatory T-cells for prevention of graft versus host disease in allogeneic hematopoietic stem cell transplantation: feasibility, safety and immune reconstitution

Incubation of umbilical cord blood (UCB) derived regulatory T-cells (Tregs) with fucosyltransferase enzyme improves their ability to home to the target tissue to prevent graft vs. host disease (GVHD). We report results of 5 patients (Double UCB Transplant, n=2; Peripheral Blood Matched Unrelated Don...

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Detalles Bibliográficos
Autores principales: Kellner, Joshua N., Delemarre, Eveline M., Yvon, Eric, Nierkens, Stefan, Boelens, Jaap J., McNiece, Ian, Olson, Amanda, Nieto, Yago, Ciurea, Stefan, Popat, Uday, Ahmed, Sairah, Champlin, Richard, Ramos, Jennifer, Nishimoto, Mitsutaka, Ma, Hongbing, Ke, Zeng, Thall, Peter, Khoury, Joseph D., Negrin, Robert, Andersson, Borje, Parmar, Simrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235025/
https://www.ncbi.nlm.nih.gov/pubmed/30479692
http://dx.doi.org/10.18632/oncotarget.26242

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