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DVL1 and DVL3 differentially localize to CYP19A1 promoters and regulate aromatase mRNA in breast cancer cells
The CYP19A1 gene encodes aromatase, an enzyme that converts androgens into estrogens and consequently directly contributes to both the depletion of androgens and the synthesis of estrogens in several organs. Aromatase is critical for diverse biological processes such as proliferation, regulation of...
Autores principales: | Castro-Piedras, Isabel, Sharma, Monica, den Bakker, Meghan, Molehin, Deborah, Martinez, Edgar G., Vartak, David, Pruitt, Wendy M., Deitrick, Jena, Almodovar, Sharilyn, Pruitt, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235026/ https://www.ncbi.nlm.nih.gov/pubmed/30479694 http://dx.doi.org/10.18632/oncotarget.26257 |
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