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Mealtime dosing of a rapid-acting insulin analog reduces glucose variability and suppresses daytime cardiac sympathetic activity: a randomized controlled study in hospitalized patients with type 2 diabetes

OBJECTIVE: Glucose variability induces endothelial dysfunction and cardiac autonomic nerve abnormality. Here we compared the effects of mealtime insulin aspart and bedtime insulin detemir on glucose variability, endothelial function, and cardiac autonomic nerve activity among Japanese patients with...

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Detalles Bibliográficos
Autores principales:	Kanamori, Takehiro, Takeshita, Yumie, Isobe, Yuki, Kato, Ken-ichiro, Misu, Hirofumi, Kaneko, Shuichi, Takamura, Toshinari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Cardiovascular and Metabolic Risk
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235056/ https://www.ncbi.nlm.nih.gov/pubmed/30487974 http://dx.doi.org/10.1136/bmjdrc-2018-000588

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