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Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation

BACKGROUND: Neutrophil extracellular trap (NET) formation has been described to be closely involved in the pathogenesis of systemic lupus erythematosus (SLE). In this study, we aimed to investigate the effect of polydatin (PD) on NET formation and its effects on disease activity in lupus-prone mouse...

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Detalles Bibliográficos
Autores principales:	Liao, Pan, He, Yi, Yang, Fangyuan, Luo, Guihu, Zhuang, Jian, Zhai, Zeqing, Zhuang, Lili, Lin, Zhuomiao, Zheng, Jiehuang, Sun, Erwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235205/ https://www.ncbi.nlm.nih.gov/pubmed/30419963 http://dx.doi.org/10.1186/s13075-018-1749-y

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