Cargando…

Lupeol inhibits growth and migration in two human colorectal cancer cell lines by suppression of Wnt–β-catenin pathway

BACKGROUND: Lupeol, a triterpene isolated from various herbal plants, possesses an anti-inflammatory function and has been proposed as a candidate for anticancer agents. The purpose of this research was to investigate the effect of lupeol on the viability, apoptosis, cell-cycle distribution, and mig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yihao, Hong, Dan, Qian, Yuqin, Tu, Xuezi, Wang, Keke, Yang, Xianhong, Shao, Sijia, Kong, Xinlong, Lou, Zhefeng, Jin, Longjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235339/ https://www.ncbi.nlm.nih.gov/pubmed/30519040 http://dx.doi.org/10.2147/OTT.S183925

Ejemplares similares

Lupeol Inhibits Growth and Migration in Two Human Colorectal Cancer Cell Lines by Suppression of Wnt–β-Catenin Pathway [Retraction]
Publicado: (2020)

Lupeol Accumulation Correlates with Auxin in the Epidermis of Castor
por: Li, Donghai, et al.
Publicado: (2021)

DAB2 suppresses gastric cancer migration by regulating the Wnt/β-catenin and Hippo-YAP signaling pathways
por: Wang, Hua, et al.
Publicado: (2020)

Drosophila Perlecan Regulates Intestinal Stem Cell Activity via Cell-Matrix Attachment
por: You, Jia, et al.
Publicado: (2014)

Screening of Filamentous Fungi to Identify Biocatalysts for Lupeol Biotransformation
por: de Carvalho, Tatiane C., et al.
Publicado: (2010)

Molecular docking analysis of lupeol with different cancer targets
por: Gunasekaran, Mahalakshmi, et al.
Publicado: (2022)

Nerve growth factor modulates the tumor cells migration in ovarian cancer through the WNT/β-catenin pathway
por: Li, Bo, et al.
Publicado: (2016)

Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer
por: Ma, Yanmei, et al.
Publicado: (2021)

Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer
por: Ma, Yanmei, et al.
Publicado: (2022)

New lupeol esters as active substances in the treatment of skin damage
por: Malinowska, Magdalena, et al.
Publicado: (2019)

Isolation of lupeol acetate from fruit peels of Artocarpus camansi
por: Nasution, Rosnani, et al.
Publicado: (2020)

In vitro and in vivo antitumor effects of lupeol-loaded galactosylated liposomes
por: Zhang, Jun, et al.
Publicado: (2021)

Investigation of Lupeol as Anti-Melanoma Agent: An In Vitro-In Ovo Perspective
por: Bociort, Flavia, et al.
Publicado: (2021)

In vitro evaluation of anticancer potentials of lupeol isolated from Elephantopus scaber L. on MCF-7 cell line
por: Pitchai, Daisy, et al.
Publicado: (2014)

TIPE1 suppresses invasion and migration through down‐regulating Wnt/β‐catenin pathway in gastric cancer
por: Liu, Wenwen, et al.
Publicado: (2017)

ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling
por: Sun, Xiaoyun, et al.
Publicado: (2020)

Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells
por: Chen, Changbao, et al.
Publicado: (2015)

Running Against the Wnt: How Wnt/β-Catenin Suppresses Adipogenesis
por: de Winter, Twan J. J., et al.
Publicado: (2021)

Differentiation-inducing and anti-proliferative activities of lupeol on canine melanoma cells
por: Ogihara, Kikumi, et al.
Publicado: (2014)

Comparative study of anti-angiogenic activities of luteolin, lectin and lupeol biomolecules
por: Ambasta, Rashmi K., et al.
Publicado: (2015)

Lupeol Stearate Accelerates Healing and Prevents Recurrence of Gastric Ulcer in Rodents
por: Somensi, Lincon Bordignon, et al.
Publicado: (2022)

Lupeol alters viability of SK-RC-45 (Renal cell carcinoma cell line) by modulating its mitochondrial dynamics
por: Sinha, Krishnendu, et al.
Publicado: (2019)

Aloe-emodin inhibits the proliferation, migration, and invasion of melanoma cells via inactivation of the Wnt/beta-catenin signaling pathway
por: Du, Maotao, et al.
Publicado: (2021)

Sanguinarine suppresses migration and metastasis in colorectal carcinoma associated with the inversion of EMT through the Wnt/β‐catenin signaling
por: Zhu, Man, et al.
Publicado: (2020)

Wnt/β-Catenin Signaling and Obesity
por: Chen, Na, et al.
Publicado: (2018)

Improving lupeol production in yeast by recruiting pathway genes from different organisms
por: Qiao, Weibo, et al.
Publicado: (2019)

The pentacyclic triterpenoid phytosterol lupeol promotes antioxidant response in the nematode C. elegans
por: Voia, Anna, et al.
Publicado: (2022)

Emodin Inhibits Colon Cancer Cell Invasion and Migration by Suppressing Epithelial–Mesenchymal Transition via the Wnt/β-Catenin Pathway
por: Gu, Juan, et al.
Publicado: (2019)

Cir-ITCH inhibits gastric cancer migration, invasion and proliferation by regulating the Wnt/β-catenin pathway
por: Peng, Yang, et al.
Publicado: (2020)

Knock-Down of HOXB8 Prohibits Proliferation and Migration of Colorectal Cancer Cells via Wnt/β-Catenin Signaling Pathway
por: Li, Xiang, et al.
Publicado: (2019)

TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling
por: Liu, Feng, et al.
Publicado: (2023)

MicroRNA-200a suppresses the Wnt/β-catenin signaling pathway by interacting with β-catenin
por: SU, JUAN, et al.
Publicado: (2011)

Lupeol Alleviates Cerebral Ischemia–Reperfusion Injury in Correlation with Modulation of PI3K/Akt Pathway
por: Wang, Zhiwei, et al.
Publicado: (2020)

MicroRNA-216a suppresses the proliferation and migration of human breast cancer cells via the Wnt/β-catenin signaling pathway
por: Xie, Qing, et al.
Publicado: (2019)

Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway
por: Liu, Qian-Qian, et al.
Publicado: (2016)

Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling
por: Herbst, Andreas, et al.
Publicado: (2014)

Isolation and high-performance thin layer chromatographic estimation of Lupeol from Oxystelma esculentum
por: Pandya, Devang J., et al.
Publicado: (2011)

Balanophora spicata and Lupeol Acetate Possess Antinociceptive and Anti-Inflammatory Activities In Vivo and In Vitro
por: Chen, Yuh-Fung, et al.
Publicado: (2012)

LASP2 suppressed malignancy and Wnt/β-catenin signaling pathway activation in bladder cancer
por: Yang, Rongquan, et al.
Publicado: (2018)

Molecular hydrogen suppresses activated Wnt/β-catenin signaling
por: Lin, Yingni, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_c4ur4ugn8ubm34asl84ktiamod