Cargando…

Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas

We report the case of a 13-year old female patient from rural areas presenting with papulonodular lesion of 4/3cm in the lower third of the right leg, evolving over the last two years. Skin biopsy showed papillomatous hyperplasia with neutrophilic microabscess and spores. Direct mycological examinat...

Descripción completa

Detalles Bibliográficos
Autores principales: Baline, Kenza, Hali, Fouzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235512/
https://www.ncbi.nlm.nih.gov/pubmed/30455816
http://dx.doi.org/10.11604/pamj.2018.30.187.5326
_version_ 1783370885000855552
author Baline, Kenza
Hali, Fouzia
author_facet Baline, Kenza
Hali, Fouzia
author_sort Baline, Kenza
collection PubMed
description We report the case of a 13-year old female patient from rural areas presenting with papulonodular lesion of 4/3cm in the lower third of the right leg, evolving over the last two years. Skin biopsy showed papillomatous hyperplasia with neutrophilic microabscess and spores. Direct mycological examination showed fumagoid bodies and Fonsecaea pedrosoi was isolated from culture. The patient underwent medico-surgical treatment (terbinafine 250mg/day for 6 months + resection and then skin graft) with good evolution and a follow-up period of 2 years without recurrences. Chromoblastomycosis is a chronic fungal skin infection, common in tropical and subtropical areas and rare in North Africa. In Morocco, only seven cases have been reported in the literature until June 2014. It is contracted from inoculation of germ after contact with the soil or organic matters. Responsible officers are pigmented fungi belonging to the dematiated group. Given its rarity, it can mimic other dermatoses such as leishmaniasis or tuberculosis. Despite the rarity of this infection, clinicians should suspect it in patients with chronic skin lesions (verrucous, vegetative, nodular and grouped in patches), especially if they occur in areas exposed to potential plant injuries, such as the lower limbs. Mycological examination is necessary to confirm the diagnosis. Surgery or the association between surgery and systemic antifungal drugs are the treatments of choice because antifungal drugs alone may result in resistances or recurrences.
format Online
Article
Text
id pubmed-6235512
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher The African Field Epidemiology Network
record_format MEDLINE/PubMed
spelling pubmed-62355122018-11-19 Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas Baline, Kenza Hali, Fouzia Pan Afr Med J Images in Medicine We report the case of a 13-year old female patient from rural areas presenting with papulonodular lesion of 4/3cm in the lower third of the right leg, evolving over the last two years. Skin biopsy showed papillomatous hyperplasia with neutrophilic microabscess and spores. Direct mycological examination showed fumagoid bodies and Fonsecaea pedrosoi was isolated from culture. The patient underwent medico-surgical treatment (terbinafine 250mg/day for 6 months + resection and then skin graft) with good evolution and a follow-up period of 2 years without recurrences. Chromoblastomycosis is a chronic fungal skin infection, common in tropical and subtropical areas and rare in North Africa. In Morocco, only seven cases have been reported in the literature until June 2014. It is contracted from inoculation of germ after contact with the soil or organic matters. Responsible officers are pigmented fungi belonging to the dematiated group. Given its rarity, it can mimic other dermatoses such as leishmaniasis or tuberculosis. Despite the rarity of this infection, clinicians should suspect it in patients with chronic skin lesions (verrucous, vegetative, nodular and grouped in patches), especially if they occur in areas exposed to potential plant injuries, such as the lower limbs. Mycological examination is necessary to confirm the diagnosis. Surgery or the association between surgery and systemic antifungal drugs are the treatments of choice because antifungal drugs alone may result in resistances or recurrences. The African Field Epidemiology Network 2018-06-28 /pmc/articles/PMC6235512/ /pubmed/30455816 http://dx.doi.org/10.11604/pamj.2018.30.187.5326 Text en © Kenza Baline et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Images in Medicine
Baline, Kenza
Hali, Fouzia
Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas
title Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas
title_full Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas
title_fullStr Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas
title_full_unstemmed Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas
title_short Chromomycose cutanée à Fonsecaea Pedrosoi: à propos d’un cas
title_sort chromomycose cutanée à fonsecaea pedrosoi: à propos d’un cas
topic Images in Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235512/
https://www.ncbi.nlm.nih.gov/pubmed/30455816
http://dx.doi.org/10.11604/pamj.2018.30.187.5326
work_keys_str_mv AT balinekenza chromomycosecutaneeafonsecaeapedrosoiaproposduncas
AT halifouzia chromomycosecutaneeafonsecaeapedrosoiaproposduncas