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Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme

Glycogen is the primary storage form of glucose. Glycogen synthesis and breakdown are tightly controlled by glycogen synthase (GYS) and phosphorylase, respectively. The enzyme responsible for dephosphorylating GYS and phosphorylase, which results in their activation (GYS) or inactivation (phosphoryl...

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Detalles Bibliográficos
Autores principales: Kumar, Ganesan Senthil, Choy, Meng S., Koveal, Dorothy M., Lorinsky, Michael K., Lyons, Scott P., Kettenbach, Arminja N., Page, Rebecca, Peti, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235537/
https://www.ncbi.nlm.nih.gov/pubmed/30443599
http://dx.doi.org/10.1126/sciadv.aau6044