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Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme
Glycogen is the primary storage form of glucose. Glycogen synthesis and breakdown are tightly controlled by glycogen synthase (GYS) and phosphorylase, respectively. The enzyme responsible for dephosphorylating GYS and phosphorylase, which results in their activation (GYS) or inactivation (phosphoryl...
Autores principales: | Kumar, Ganesan Senthil, Choy, Meng S., Koveal, Dorothy M., Lorinsky, Michael K., Lyons, Scott P., Kettenbach, Arminja N., Page, Rebecca, Peti, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235537/ https://www.ncbi.nlm.nih.gov/pubmed/30443599 http://dx.doi.org/10.1126/sciadv.aau6044 |
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