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Cryo-EM structure of the mechanically activated ion channel OSCA1.2

Mechanically activated ion channels underlie touch, hearing, shear-stress sensing, and response to turgor pressure. OSCA/TMEM63s are a newly-identified family of eukaryotic mechanically activated ion channels opened by membrane tension. The structural underpinnings of OSCA/TMEM63 function are not ex...

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Detalles Bibliográficos
Autores principales:	Jojoa-Cruz, Sebastian, Saotome, Kei, Murthy, Swetha E, Tsui, Che Chun Alex, Sansom, Mark SP, Patapoutian, Ardem, Ward, Andrew B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235563/ https://www.ncbi.nlm.nih.gov/pubmed/30382939 http://dx.doi.org/10.7554/eLife.41845

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