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Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female

A poorly feeding neonate presents the clinician with a diagnostic challenge. Feeding difficulties and irritability may be due to sepsis, congenital heart disease, inborn errors of metabolism, non-accidental head trauma, as well as a vast variety of other pathologies. Teratomas are rare pediatric tum...

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Detalles Bibliográficos
Autores principales: Rainey, Shane C, Kandikattu, Bhavana S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235640/
https://www.ncbi.nlm.nih.gov/pubmed/30443451
http://dx.doi.org/10.7759/cureus.3281
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author Rainey, Shane C
Kandikattu, Bhavana S
author_facet Rainey, Shane C
Kandikattu, Bhavana S
author_sort Rainey, Shane C
collection PubMed
description A poorly feeding neonate presents the clinician with a diagnostic challenge. Feeding difficulties and irritability may be due to sepsis, congenital heart disease, inborn errors of metabolism, non-accidental head trauma, as well as a vast variety of other pathologies. Teratomas are rare pediatric tumors that can occasionally present in the immediate neonatal period and can manifest in the infant's central nervous system (CNS) with non-specific symptoms of poor feeding, lethargy, and somnolence. Operative resection remains the cornerstone of treatment; however, there is no well-defined role for adjuvant chemotherapy or radiation in these treatments. We report a case of a four-week-old female presenting with progressive feeding intolerance secondary to a near holocord thoracic spinal teratoma. Her tumor was surgically resected and she was treated with adjuvant chemotherapy and radiation for 13 months and is now in clinical remission. While rare, intramedullary spinal cord lesions should be considered in the differential diagnosis of infants presenting with poor feeding and hypotonia.
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spelling pubmed-62356402018-11-15 Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female Rainey, Shane C Kandikattu, Bhavana S Cureus Pediatrics A poorly feeding neonate presents the clinician with a diagnostic challenge. Feeding difficulties and irritability may be due to sepsis, congenital heart disease, inborn errors of metabolism, non-accidental head trauma, as well as a vast variety of other pathologies. Teratomas are rare pediatric tumors that can occasionally present in the immediate neonatal period and can manifest in the infant's central nervous system (CNS) with non-specific symptoms of poor feeding, lethargy, and somnolence. Operative resection remains the cornerstone of treatment; however, there is no well-defined role for adjuvant chemotherapy or radiation in these treatments. We report a case of a four-week-old female presenting with progressive feeding intolerance secondary to a near holocord thoracic spinal teratoma. Her tumor was surgically resected and she was treated with adjuvant chemotherapy and radiation for 13 months and is now in clinical remission. While rare, intramedullary spinal cord lesions should be considered in the differential diagnosis of infants presenting with poor feeding and hypotonia. Cureus 2018-09-11 /pmc/articles/PMC6235640/ /pubmed/30443451 http://dx.doi.org/10.7759/cureus.3281 Text en Copyright © 2018, Rainey et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Rainey, Shane C
Kandikattu, Bhavana S
Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female
title Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female
title_full Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female
title_fullStr Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female
title_full_unstemmed Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female
title_short Progressive Feeding Intolerance Secondary to a Congenital Spinal Teratoma in a Four-week-old Female
title_sort progressive feeding intolerance secondary to a congenital spinal teratoma in a four-week-old female
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235640/
https://www.ncbi.nlm.nih.gov/pubmed/30443451
http://dx.doi.org/10.7759/cureus.3281
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