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An mTOR Signaling Modulator Suppressed Heterotopic Ossification of Fibrodysplasia Ossificans Progressiva

Fibrodysplasia ossificans progressiva (FOP) is a rare and intractable disorder characterized by extraskeletal bone formation through endochondral ossification. FOP patients harbor gain-of-function mutations in ACVR1 (FOP-ACVR1), a type I receptor for bone morphogenetic proteins. Despite numerous stu...

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Detalles Bibliográficos
Autores principales:	Hino, Kyosuke, Zhao, Chengzhu, Horigome, Kazuhiko, Nishio, Megumi, Okanishi, Yasue, Nagata, Sanae, Komura, Shingo, Yamada, Yasuhiro, Toguchida, Junya, Ohta, Akira, Ikeya, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235670/ https://www.ncbi.nlm.nih.gov/pubmed/30392977 http://dx.doi.org/10.1016/j.stemcr.2018.10.007

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