Cargando…

NTG-101: A Novel Molecular Therapy that Halts the Progression of Degenerative Disc Disease

The tremendous cost, pain and disability associated with degenerative disc disease (DDD) makes the development of a biological agent that can mitigate the course of DDD, a critical unmet need. We have identified and reported that a single injection of a combination of recombinant human (rh) Transfor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matta, Ajay, Karim, Muhammad Zia, Gerami, Hoda, Jun, Peter, Funabashi, Martha, Kawchuk, Greg, Goldstein, Alyssa, Foltz, Warren, Sussman, Marshall, Eek, Bjorn C., Erwin, W. Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235869/ https://www.ncbi.nlm.nih.gov/pubmed/30429487 http://dx.doi.org/10.1038/s41598-018-35011-4

Ejemplares similares

A comparative study of mesenchymal stem cell transplantation and NTG-101 molecular therapy to treat degenerative disc disease
por: Matta, Ajay, et al.
Publicado: (2021)

A Single Injection of NTG-101 Reduces the Expression of Pain-Related Neurotrophins in a Canine Model of Degenerative Disc Disease
por: Matta, Ajay, et al.
Publicado: (2022)

The biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc
por: Erwin, William Mark, et al.
Publicado: (2015)

Injectable Biologics for the Treatment of Degenerative Disc Disease
por: Matta, Ajay, et al.
Publicado: (2020)

Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus
por: Matta, Ajay, et al.
Publicado: (2017)

Nontoxic Goiter (NTG) and Radioiodine: What Do Patients Think About It? Quality of Life in Patients with NTG Before and After 131-I Therapy
por: Kaniuka-Jakubowska, Sonia, et al.
Publicado: (2018)

Data Networks with Satellites: Working Conference of the Joint GI/NTG
por: Majus, Joachim, et al.
Publicado: (1983)

Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice
por: Casili, Giovanna, et al.
Publicado: (2020)

Association of OPA1 Polymorphisms with NTG and HTG: A Meta-Analysis
por: Guo, Yatu, et al.
Publicado: (2012)

Studies on the Mechanism of Glutamate Metabolism in NTG-Induced Migraine Rats Treated with DCXF
por: Ni, Ni, et al.
Publicado: (2019)

Current Status of the Instructional Cues Provided by Notochordal Cells in Novel Disc Repair Strategies
por: Matta, Ajay, et al.
Publicado: (2021)

Analysis of association between MALAT1 haplotype and the severity of normal‐tension glaucoma (NTG)
por: Yue, Jin‐liang, et al.
Publicado: (2021)

Comparison of Retinal Nerve Fiber Layer Measurements between NTG and HTG using GDx-VCC
por: Jung, Ji Yong, et al.
Publicado: (2006)

Pathophysiology of Degenerative Disc Disease
por: Choi, Yong-Soo
Publicado: (2009)

Total Disc Replacement in Lumbar Degenerative Disc Diseases
por: Park, Chun Kun
Publicado: (2015)

Putting a Halt to HALT: Does Anticoagulation Matter?
por: DeAnda, Abe, et al.
Publicado: (2022)

Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress
por: Swartzlander, Dan B., et al.
Publicado: (2010)

Total Disc Arthroplasty for Treating Lumbar Degenerative Disc Disease
por: Mostofi, Keyvan
Publicado: (2015)

Diagnostic Testing for Degenerative Disc Disease
por: Hasz, Michael W.
Publicado: (2012)

Analysis of crucial molecules involved in herniated discs and degenerative disc disease
por: Qu, Zhigang, et al.
Publicado: (2013)

SCFA Treatment Alleviates Pathological Signs of Migraine and Related Intestinal Alterations in a Mouse Model of NTG-Induced Migraine
por: Lanza, Marika, et al.
Publicado: (2021)

Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine
por: Lanza, Marika, et al.
Publicado: (2022)

Stem Cell Therapy for Degenerative Disc Disease
por: Drazin, Doniel, et al.
Publicado: (2012)

Operative Management of Lumbar Degenerative Disc Disease
por: Lee, Yu Chao, et al.
Publicado: (2016)

The Role of Sex Hormones in Degenerative Disc Disease
por: Shelby, Tara, et al.
Publicado: (2023)

Halting the Allergic March
por: Van Bever, Hugo P, et al.
Publicado: (2008)

Halting coronavirus polymerase
por: Kirchdoerfer, Robert N.
Publicado: (2020)

Halting 'research waste'
por: Shamsoddin, E., et al.
Publicado: (2021)

A Halt Called
Publicado: (1897)

An organ culture system to model early degenerative changes of the intervertebral disc
por: Ponnappan, Ravi K, et al.
Publicado: (2011)

Inhibition of glutamatergic trigeminal nucleus caudalis- vestibular nucleus projection neurons attenuates vestibular dysfunction in the chronic-NTG model of migraine
por: Zhang, Yun, et al.
Publicado: (2023)

Advances in Susceptibility Genetics of Intervertebral Degenerative Disc Disease
por: Zhang, Yin'gang, et al.
Publicado: (2008)

Impact of changes in extracellular matrix in the lumbar degenerative disc
por: David, G, et al.
Publicado: (2011)

Genetic background of degenerative disc disease in the lumbar spine
por: Kawaguchi, Yoshiharu
Publicado: (2018)

The characteristics of stem cells in human degenerative intervertebral disc
por: Liang, Lin, et al.
Publicado: (2017)

A Brief Review of the Degenerative Intervertebral Disc Disease
por: Kos, Natasa, et al.
Publicado: (2019)

Computed tomography osteoabsorptiometry for imaging of degenerative disc disease
por: Gay, Max Hans-Peter, et al.
Publicado: (2022)

Modeling the impact of xenointoxication in dogs to halt Trypanosoma cruzi transmission
por: Rokhsar, Jennifer L., et al.
Publicado: (2023)

Modeling the impact of xenointoxication in dogs to halt Trypanosoma cruzi transmission
por: Rokhsar, Jennifer L., et al.
Publicado: (2023)

Lumbar Disc Degenerative Disease: Disc Degeneration Symptoms and Magnetic Resonance Image Findings
por: Saleem, Shafaq, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_n6qe55frl9790vn1m7q356p51l