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The Role of TNF-α induced MSCs on Suppressive Inflammation by Increasing TGF-β and IL-10
BACKGROUND: Mesenchymal stem cells (MSCs) may serve as immunoregulators by producing various anti-inflammatory molecules. Under sufficient level of TNF-α, MSCs become activated and adopt immune-suppressive phenotype (MSCs type-2) by releasing various anti-inflammatory molecule including TGF-β and IL...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Republic of Macedonia
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236029/ https://www.ncbi.nlm.nih.gov/pubmed/30455748 http://dx.doi.org/10.3889/oamjms.2018.404 |