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Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway

Acute kidney injury (AKI) is a clinically common and severe complication of ischemia-reperfusion (I/R), associated with high morbidity and mortality rates, and prolonged hospitalization. Rapamycin is a type of macrolide, primarily used for anti-rejection therapy following organ transplantation and t...

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Detalles Bibliográficos
Autores principales: Su, Yang, Lu, Jingxiao, Gong, Pian, Chen, Xianguo, Liang, Chaozhao, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236225/
https://www.ncbi.nlm.nih.gov/pubmed/30365078
http://dx.doi.org/10.3892/mmr.2018.9586