Cargando…

Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP-induced Parkinson's disease models in vitro and in vivo

The pathological alterations of Parkinson's disease (PD) predominantly manifest as a loss of dopaminergic neurons in the substantia nigra, which may be caused by oxidative stress damage. Proanthocyanidins (PCs) are a class of compounds found in various plants, which have significant antioxidant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Hucheng, Xu, Jiyu, Lv, Yuan, He, Ping, Liu, Chunyan, Jiao, Jie, Li, Shiwei, Mao, Xuhua, Xue, Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236276/ https://www.ncbi.nlm.nih.gov/pubmed/30272275 http://dx.doi.org/10.3892/mmr.2018.9509

Ejemplares similares

Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson’s Disease
por: Wang, Li-Yuan, et al.
Publicado: (2019)

Curcumin Regulates Gut Microbiota and Exerts a Neuroprotective Effect in the MPTP Model of Parkinson's Disease
por: Zhu, Hong, et al.
Publicado: (2022)

Echinocystic Acid Inhibits Inflammation and Exerts Neuroprotective Effects in MPTP-Induced Parkinson’s Disease Model Mice
por: He, Dewei, et al.
Publicado: (2022)

Pretreatment of caffeine leads to partial neuroprotection in MPTP model of Parkinson's disease
por: Bagga, Puneet, et al.
Publicado: (2016)

The Neuroprotective Effects of Cinnamic Aldehyde in an MPTP Mouse Model of Parkinson’s Disease
por: Bae, Woom-Yee, et al.
Publicado: (2018)

Preparation and Neuroprotective Activity of Glucuronomannan Oligosaccharides in an MPTP-Induced Parkinson’s Model
por: Liu, Yingjuan, et al.
Publicado: (2020)

Necrosulfonamide exerts neuroprotective effect by inhibiting necroptosis, neuroinflammation, and α-synuclein oligomerization in a subacute MPTP mouse model of Parkinson’s disease
por: Leem, Yea-Hyun, et al.
Publicado: (2023)

Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP(+)/MPTP Models of Parkinson's Disease In Vitro and In Vivo
por: Lo, Yi-Ching, et al.
Publicado: (2012)

Acylated but not des‐acyl ghrelin is neuroprotective in an MPTP mouse model of Parkinson's disease
por: Bayliss, Jacqueline A., et al.
Publicado: (2016)

Anti-Inflammatory and Neuroprotective Effects of Morin in an MPTP-Induced Parkinson’s Disease Model
por: Hong, Dong Geun, et al.
Publicado: (2022)

Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury
por: Liu, Wen-zhao, et al.
Publicado: (2022)

TFP5/TP5 peptide provides neuroprotection in the MPTP model of Parkinson's disease
por: Binukumar, BK, et al.
Publicado: (2016)

Neuroprotective and Anti-Inflammatory Effects of Evernic Acid in an MPTP-Induced Parkinson’s Disease Model
por: Lee, Seulah, et al.
Publicado: (2021)

Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration
por: Mannino, Deborah, et al.
Publicado: (2023)

Nicotine alleviates MPTP-induced nigrostriatal damage through modulation of JNK and ERK signaling pathways in the mice model of Parkinson’s disease
por: Ruan, Sisi, et al.
Publicado: (2023)

Neuroprotective Effects of Bifidobacterium breve CCFM1067 in MPTP-Induced Mouse Models of Parkinson’s Disease
por: Li, Tiantian, et al.
Publicado: (2022)

A novel small positive allosteric modulator of neuropeptide receptor PAC1-R exerts neuroprotective effects in MPTP mouse Parkinson’s disease model: A new drug for Parkinson’s disease
por: Fan, Guangchun, et al.
Publicado: (2022)

Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota
por: Zhou, Xiaoting, et al.
Publicado: (2021)

Characterization of Nasco grape pomace-loaded nutriosomes and their neuroprotective effects in the MPTP mouse model of Parkinson’s disease
por: Parekh, Pathik, et al.
Publicado: (2022)

Electroacupuncture exerts neuroprotective effects on ischemia/reperfusion injury in JNK knockout mice: the underlying mechanism
por: Wu, Chun-Xiao, et al.
Publicado: (2018)

Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson’s Disease
por: Liu, Mei-Fang, et al.
Publicado: (2018)

p-Hydroxybenzyl Alcohol Antagonized the ROS-Dependent JNK/Jun/Caspase-3 Pathway to Produce Neuroprotection in a Cellular Model of Parkinson’s Disease
por: Lai, Mei-Chou, et al.
Publicado: (2022)

Neuroprotective Effects of Tetramethylpyrazine against Dopaminergic Neuron Injury in a Rat Model of Parkinson's Disease Induced by MPTP
por: Lu, Chen, et al.
Publicado: (2014)

Interleukin 4-induced neuroprotection and regulation of microglia activation as a therapeutic approach in the MPTP model of Parkinson's disease
por: Spittau, Björn
Publicado: (2017)

Neuroprotective and Neurorestorative Effects of Holothuria scabra Extract in the MPTP/MPP(+)-Induced Mouse and Cellular Models of Parkinson’s Disease
por: Noonong, Kunwadee, et al.
Publicado: (2020)

Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS
por: Leem, Yea-Hyun, et al.
Publicado: (2021)

Remote tissue conditioning is neuroprotective against MPTP insult in mice
por: Kim, Boaz, et al.
Publicado: (2018)

Neuroprotective Effects of Lindleyin on Hydrogen Peroxide-Induced Cell Injury and MPTP-Induced Parkinson's Disease in C57BL/6 Mice
por: Zhang, Jin-Jie, et al.
Publicado: (2020)

Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson’s disease
por: DAI, TING-LI, et al.
Publicado: (2014)

Fisetin Regulates Gut Microbiota and Exerts Neuroprotective Effect on Mouse Model of Parkinson’s Disease
por: Chen, Tian-Jiao, et al.
Publicado: (2020)

Arctigenin Exerts Neuroprotective Effect by Ameliorating Cortical Activities in Experimental Autoimmune Encephalomyelitis In Vivo
por: Wei, Liangpeng, et al.
Publicado: (2021)

Neuroprotective Effects of β-Caryophyllene against Dopaminergic Neuron Injury in a Murine Model of Parkinson’s Disease Induced by MPTP
por: Viveros-Paredes, Juan M., et al.
Publicado: (2017)

Astrocytic Nrf2 Mediates the Neuroprotective and Anti-Inflammatory Effects of Nootkatone in an MPTP-Induced Parkinson’s Disease Mouse Model
por: Park, Jung-Eun, et al.
Publicado: (2023)

Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo
por: Zhou, Hefeng, et al.
Publicado: (2019)

Neuroprotective Effects and Related Mechanisms of Echinacoside in MPTP-Induced PD Mice
por: Zhang, Zhen-Nian, et al.
Publicado: (2021)

Moxibustion Exerts a Neuroprotective Effect through Antiferroptosis in Parkinson's Disease
por: Lu, Juan, et al.
Publicado: (2019)

Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D(3 )receptor
por: Joyce, Jeffrey N, et al.
Publicado: (2004)

Neuroprotective changes in degeneration-related gene expression in the substantia nigra following acupuncture in an MPTP mouse model of Parkinsonism: Microarray analysis
por: Yeo, Sujung, et al.
Publicado: (2015)

Dose-Dependent Neuroprotective Effect of Standardized Bee Venom Phospholipase A(2) Against MPTP-Induced Parkinson’s Disease in Mice
por: Kim, Kyung Hwa, et al.
Publicado: (2019)

Deficiency of miR-29b2/c leads to accelerated aging and neuroprotection in MPTP-induced Parkinson’s disease mice
por: Bai, Xiaochen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7h20om45e07tmqennfs9tfh9be